Kate Moss splits from rock guitarist boyfriend Jamie Hince

Kate Moss has split with her rockstar boyfriend Jamie Hince after a series of arguments which left the supermodel in tears at London Fashion Week.

It is believed The Kills guitarist was unhappy about Moss’ non-stop party lifestyle.

The pair have split three times before but friends say this time the break-up is serious.

"Kate thinks there is no going back this time and has told Jamie to keep away from her," a friend was reported as saying.

"Although she has said that before, she has never appeared as hurt as this and the rows have never been this bad."

Rumours began circulating when Moss failed to show at a number of exclusive parties during London Fashion Week.

When she did appear for the Vivienne Westwood Red Label show she was photographed smoking and crying on her own.

A source from the show said: “Kate was in tears at Vivienne’s show and told a number of close fashion industry friends that it was over.

"Jamie told her he was fed-up with her reluctance to stop partying and focus on normality. We have heard it all before but this time friends felt her attitude was very different.

"They just don’t see eye-to-eye. When their relationship is good it’s amazing but when its bad it’s a tragedy."

The couple, who recently were seen sporting matching anchor tattoos, are thought to have split early last week.

Moss and Hince met last September shortly after Kate ended her relationship with troubled Babyshambles frontman Pete Doherty